Open PHACTS Phenotypic Screening Workshop

On 16-17 February, 2015, Open PHACTS successfully held a workshop in Santiago de Compostela (Spain) entitled “Understanding the knowledge management needs of phenotypic screening”. Read about the workshop and its outcomes

Open PHACTS New Releases and API v1.3 decommission

On February 19, 2015, Posted by , In News, By , , With No Comments

This quarter we are planning new releases in Open PHACTS including updates to our API (version 1.4), new functionality and new data. We will release more information about this soon. As part of these plans, we will be decommissioning an older API, version 1.3. This version will be switched off by the…

Open PHACTS PLoS ONE publication

On December 18, 2014, Posted by , In News, By ,, , With No Comments

Some great examples of how Open PHACTS can help solve drug discovery problems have just been published in the open access journal PLOS ONE: The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research

Job Opportunity: OPF Technical and Strategic Coordinator

On December 9, 2014, Posted by , In News, By ,, , With No Comments

An exciting opportunity for an experienced pharma/life-science professional to join the Open PHACTS Foundation as technical strategic co-ordinator. For more information, please see the job listing.

Open PHACTS added to the OMICtools directory

On December 9, 2014, Posted by , In News, By ,, , With No Comments

Open PHACTS has been added to the OMICtools directory of resources for biomedical researchers: http://omictools.com/open-phacts-s7428.html

Human Proteome data in RDF format

We are excited that Open PHACTS team members’ experience helped make Human Proteome data available in RDF format: http://www.proteinatlas.org/about/download

Open PHACTS API 1.4 released

On August 26, 2014, Posted by , In News, By , , With No Comments

We are excited to release Open PHACTS API version 1.4, featuring: 2 new data sets with corresponding API calls New results in Compound Information call New batch methods for Information calls Find the release notes at our support portal and try out the API at https://dev.openphacts.org.

Open PHACTS Newsletter 5

Contents: Open PHACTS Foundation announces first three members Open PHACTS project extended for another 18 months 6th Community Workshop: Open PHACTS for Academia Open PHACTS Pipeline Pilot Component Collection 2.0 and Hackathon Open PHACTS poster wins prize at CSHALS 2014 in Boston Open PHACTS Explorer updated Recent Publications Recent Event…

Update of DisGeNET RDF

On July 2, 2014, Posted by , In News, By , , With No Comments

We are pleased to announce an update to DisGeNET RDF. Please find all the new data and related information at rdf.disgenet.org.

“Open PHACTS for Academia” Community Workshop held in London

On June 26, 2014, Posted by , In News, By ,,,, , With Comments Off on “Open PHACTS for Academia” Community Workshop held in London

6th Open PHACTS Community Workshop London, UK – The sixth Open PHACTS Community Workshop focussed on introducing members of the academic community to the Open PHACTS Discovery Platform, and showing them how to use it within their research and teaching workflows. The morning session featured an introduction to the Open…

6th Open PHACTS Community Workshop is this week!

The 6th Open PHACTS Community Workshop will be held in London on 26 June 2014 and aims to introduce members of the academic community to the Open PHACTS Discovery Platform. The workshop is free to attend, please register your interest by contacting london@openphactsfoundation.org. Find full information about the workshop here.

Open PHACTS project outputs are highly cited

On April 17, 2014, Posted by , In News, By ,, , With No Comments

The Open PHACTS Impactstory profile shows project outputs to be highly discussed, saved and cited. If you have papers, data, code or websites that you’d like to include please let the PMU know at pmu@openphacts.org.

6th Open PHACTS Community Workshop

The 6th Open PHACTS Community Workshop will be held in London on 26 June 2014 and aims to introduce members of the academic community to the Open PHACTS Discovery Platform. The workshop is free to attend, please register your interest by contacting london@openphactsfoundation.org. The workshop will be of interest to: Researchers…

ChemBioNavigator updated

On March 21, 2014, Posted by , In News, By ,,, , With No Comments

We are pleased to announce that a major update of ChemBioNavigator, jointly developed by the University of Hamburg and BioSolveIT, has just been released. Among many other new features, the latest version offers the ability to use a target as a starting point and enhanced pharmacological data functionality. Please take a…

2nd Open PHACTS Pipeline Pilot Hackathon held

On 6 March, 2014, the 2nd Open PHACTS Pipeline Pilot Hackathon took place on the Merck campus in Darmstadt, Germany. Attendees from eight different industrial and academic institutions worked on the new version 2.0 of the Open PHACTS component collection which was provided by Accelrys through financial support by Janssen Pharmaceutica….

Utopia Documents integrates with Discovery Platform

Utopia Documents is a free PDF reader that connects the static content of scientific articles to the dynamic world of online content and allows data to be extracted from figures and tables within the scientific literature. Interesting concepts and words can be further investigated using a variety of tools –…

Open PHACTS Explorer updated

On February 20, 2014, Posted by , In News, By , With No Comments

The Open PHACTS Explorer now uses version 1.3 of the Open PHACTS API. This includes an update of the pharmacology data (from ChEMBL 13 to ChEMBL 16). Changes with this update: pChEMBL values (a unification over different activity types) are now available. They can be used to sort and filter…

Open PHACTS API 1.3 released

On January 24, 2014, Posted by , In News, By , , With Comments Off on Open PHACTS API 1.3 released

We are excited to release the Open PHACTS API 1.3. Among the features are: Over 2,900 million triples New compound API calls: drug type (approved, experimental) New pharmacology API calls: pChEMBL, assay type, generic name, literature DOI/PMID, target type and component New target info API calls: ChEMBL URIs, UniProt protein-protein interactions,…

Open PHACTS Newsletter 4

Contents: The Open PHACTS Foundation has joined the project Open PHACTS API Usage Students create novel applications to use the Open PHACTS API Supporting Other Initiatives GARField and Target Dossier launched Collector released Open PHACTS user support portal 5th Community Workshop: Shaping the future of Open PHACTS New Version of…

Collector released

We are pleased to announce that Collector, developed by PSMAR (Parc de Salut Mar Barcelona) is officially released. Collector uses data from the Open PHACTS Discovery Platform and the eTOX project to build QSAR predictive models. The tool features a flexible collection of filters for selecting the target, the biological data…

Award-winning Open PHACTS publications

Open PHACTS publications won the top two best paper awards at SWAT4LS 2013: Computing Identity Co-Reference Across Drug Discovery Datasets (Christian Y.A. Brenninkmeijer, Ian Dunlop, Carole Goble, Alasdair J.G. Gray, Steve Pettifer and Robert Stevens) Nanopublications for exposing experimental data in the life-sciences: a Huntingtion’s Disease case study (Eleni Mina, Mark…

New source of open chemistry patent data available

A major new source of open patent chemistry is now available, thanks to the collaboration between Digital Science and the EBI ChEMBL group. We are discussing how this data might be integrated with Open PHACTS and look forward to developing use cases in 2014.

Target Dossier released

On November 20, 2013, Posted by , In News, By ,, , With No Comments

It is our pleasure to announce the official release of Target Dossier, one of the Example Applications developed within the Open PHACTS project. The Target Dossier uses the Open PHACTS Discovery Platform to answer questions of tissue expression profiles, druggability, pathways and physiological mechanisms. Drug targets can be selected and further investigated….

Over 80% of Open PHACTS publications are open access

On November 12, 2013, Posted by , In News, By , , With No Comments

Over 80% of the publications from the Open PHACTS project are open access, available for anyone to read. A full list of our open access publications to date is below. 2013 On the formulation of performant SPARQL queries Scientific competency questions as the basis for semantically enriched open pharmacological space development…

“Shaping the future of Open PHACTS” Community Workshop held in Amsterdam

On October 18, 2013, Posted by , In News, By ,,,, , With Comments Off on “Shaping the future of Open PHACTS” Community Workshop held in Amsterdam

5th Open PHACTS Community Workshop Amsterdam, the Netherlands – This event brought together an exciting mix of participants and organisations to discuss options for future involvement with the Open PHACTS Discovery Platform and our vision for the Open PHACTS Foundation. The workshop featured talks describing the recent progress of the…

GARField launched

On October 10, 2013, Posted by , In News, By ,,, , With No Comments

We are proud to announce the launch of GARField, one of the example applications developed within Open PHACTS. GARField is an abbreviation for Graph-Activity-Relationship visualization Field and is a realisation of the Open PHACTS “Polypharmacology Browser”. It can be used to browse data in the Open PHACTS platform, with the main focus on enabling the…

Open PHACTS Support Portal Online

On October 1, 2013, Posted by , In News, By ,, , With Comments Off on Open PHACTS Support Portal Online

The Open PHACTS Support Portal is now online at support.openphacts.org.

Pipeline Pilot update

On September 26, 2013, Posted by , In News, By , , With No Comments

A new version (1.5) of the Open PHACTS Pipeline Pilot component collection is now available. Try out the new components

Open PHACTS user support

We are happy to announce that the Open PHACTS support portal is now active, including a knowledge base, a forum and a ticket system: Use the knowledge base to look up answers to frequently asked questions and search our user documentation. Use the forum to post questions and comments for…

5th Community Workshop: Shaping the future of Open PHACTS

The Open PHACTS data integration project has achieved much since 2011, and the sustainability of the service and future scientific community development are the primary subject of this meeting. To this end, the not-for-profit successor organisation for the Open PHACTS project, the Open PHACTS Foundation, has recently been established. We…