Open PHACTS Foundation

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Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS

On December 3, 2013, Posted by , In Publications, By ,,,,,,,,,,,,,,,, , With Comments Off on Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS

This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity…

Conference: Autumn School of Chemoinformatics

On November 28, 2013, Posted by , In Conferences, By ,,,,, , With Comments Off on Conference: Autumn School of Chemoinformatics

Autumn School of Chemoinformatics, Nara, Japan Marcus Gastreich (BioSolveIT GmbH) presented ChemBioNavigator

Presentation: WikiPathways: how open source code and open data can make omics technology more useful

On November 26, 2013, Posted by , In Presentations, By ,,, , With Comments Off on Presentation: WikiPathways: how open source code and open data can make omics technology more useful

Life Science Technology Event 2013, Leiden, Netherlands Chris Evelo (Maastricht University) View presentation

Conference: Life Science Technology Event

On November 26, 2013, Posted by , In Conferences, By ,,,, , With Comments Off on Conference: Life Science Technology Event

Life Science Technology Event 2013, Leiden, the Netherlands Chris Evelo (Maastricht University) gave a presentation: WikiPathways: how open source code and open data can make omics technology more useful

Publication: Pav ontology: provenance, authoring and versioning

On November 22, 2013, Posted by , In Publications, By ,,,,,, , With Comments Off on Publication: Pav ontology: provenance, authoring and versioning

We present the Provenance, Authoring and Versioning ontology (PAV): a lightweight ontology for capturing “just enough” descriptions essential for tracking the provenance, authoring and versioning of web resources. We argue that such descriptions are essential for digital scientific content. PAV distinguishes between contributors, authors and curators of content and creators…

Presentation: The biggest problem of science: Ambiguity

On November 22, 2013, Posted by , In Presentations, By ,,, , With Comments Off on Presentation: The biggest problem of science: Ambiguity

HandsOn: Biobanks 2013, The Hague, Netherlands Jan Velterop (AQnowledge) View presentation

Conference: HandsOn: Biobanks 2013

On November 21, 2013, Posted by , In Conferences, By ,,, , With Comments Off on Conference: HandsOn: Biobanks 2013

HandsOn: Biobanks 2013, The Hague, the Netherlands Jan Velterop (AQnowledge) gave a presentation: The biggest problem of science: Ambiguity

Conference: EMBL-EBI Industry Programme Workshop

On November 21, 2013, Posted by , In Conferences, By ,,,, , With Comments Off on Conference: EMBL-EBI Industry Programme Workshop

EMBL-EBI Industry Programme Workshop: Computational Tools for Chemical Biology, Phenotypic Screening and Target De-convolution, Cambridgeshire, UK Bryn Williams-Jones (Connected Discovery) represented Open PHACTS

Target Dossier released

On November 20, 2013, Posted by , In News, By ,, , With Comments Off on Target Dossier released

It is our pleasure to announce the official release of Target Dossier, one of the Example Applications developed within the Open PHACTS project. The Target Dossier uses the Open PHACTS Discovery Platform to answer questions of tissue expression profiles, druggability, pathways and physiological mechanisms. Drug targets can be selected and further investigated….

Publication: Generic Information Can Retrieve Known Biological Associations: Implications for Biomedical Knowledge Discovery

On November 19, 2013, Posted by , In Publications, By ,,,,, , With Comments Off on Publication: Generic Information Can Retrieve Known Biological Associations: Implications for Biomedical Knowledge Discovery

Weighted semantic networks built from text-mined literature can be used to retrieve known protein-protein or gene-disease associations, and have been shown to anticipate associations years before they are explicitly stated in the literature. Our text-mining system recognizes over 640,000 biomedical concepts: some are specific (i.e., names of genes or proteins)…

Project Meeting: Workshop

On November 15, 2013, Posted by , In Project Meetings, By , , With Comments Off on Project Meeting: Workshop

Testing alpha API calls (Beerse, Belgium)

Presentation: Open PHACTS Discovery Platform – Integrating pharmacological and physicochemical data

On November 15, 2013, Posted by , In Presentations, By ,,,, , With Comments Off on Presentation: Open PHACTS Discovery Platform – Integrating pharmacological and physicochemical data

Biochemical Society Workshop: Tools and Strategies to Find Chemical Probes for Your Protein, London, UK Jack Gibb (Royal Society of Chemistry) View presentation

Conference: Biochemical Society Workshop

On November 15, 2013, Posted by , In Conferences, By ,,,, , With Comments Off on Conference: Biochemical Society Workshop

Biochemical Society Workshop: Tools and Strategies to Find Chemical Probes for Your Protein, London, UK Jack Gibb (Royal Society of Chemistry) gave a presentation: Open PHACTS Discovery Platform – Integrating pharmacological and physicochemical data

Over 80% of Open PHACTS publications are open access

On November 12, 2013, Posted by , In News, By , , With Comments Off on Over 80% of Open PHACTS publications are open access

Over 80% of the publications from the Open PHACTS project are open access, available for anyone to read. A full list of our open access publications to date is below. 2013 On the formulation of performant SPARQL queries Scientific competency questions as the basis for semantically enriched open pharmacological space development…

Poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

On November 12, 2013, Posted by , In Posters, By ,,,,,,,, , With Comments Off on Poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

9th German Conference on Chemoinformatics, Fulda, Germany Katrin Stierand (University of Hamburg) View poster

Conference: 9th German Conference on Chemoinformatics

On November 12, 2013, Posted by , In Conferences, By ,,, , With Comments Off on Conference: 9th German Conference on Chemoinformatics

9th German Conference on Chemoinformatics, Fulda, Germany Katrin Stierand (University of Hamburg) presented a poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

Over 3.5 million Open PHACTS API hits since launch

On November 6, 2013, Posted by , In News, By ,, , With Comments Off on Over 3.5 million Open PHACTS API hits since launch

The Open PHACTS API has received over 3.5 million hits since its launch in January 2013.

Open PHACTS Foundation is part of proposal for IMI 9th Call

On November 5, 2013, Posted by , In News, By , , With Comments Off on Open PHACTS Foundation is part of proposal for IMI 9th Call

The recently established Open PHACTS Foundation is part of a proposal for IMI’s 9th Call: WEBAE – Leveraging Emerging Technology for Pharmacovigilance.

Over 200 Open PHACTS API users

On November 4, 2013, Posted by , In News, By ,, , With Comments Off on Over 200 Open PHACTS API users

230 individuals have registered for Open PHACTS API keys since the API launch in January 2013. If you haven’t already, sign up for your free API key now!

Open PHACTS Foundation part of a proposal for IMI’s 9th Call

On November 1, 2013, Posted by , In News, By , , With Comments Off on Open PHACTS Foundation part of a proposal for IMI’s 9th Call

The Open PHACTS Foundation is part of a proposal for IMI’s 9th Call – Leveraging Emerging Technology for Pharmacovigilance.

Managing Knowledge about Tissues IMI Workshop

On October 31, 2013, Posted by , In Community Workshops, By ,,,,,,,,, , With Comments Off on Managing Knowledge about Tissues IMI Workshop

Managing Knowledge about Tissues (Brussels, Belgium)

Presentation: Open PHACTS: How does it work? How can it work for tissue knowledge management?

On October 30, 2013, Posted by , In Presentations, By ,,, , With Comments Off on Presentation: Open PHACTS: How does it work? How can it work for tissue knowledge management?

Managing Knowledge about Tissues, Brussels, Belgium Christine Chichester (Swiss Institute of Bioinformatics) View presentation

Presentation: Knowledge management for transmembrane transporters

On October 30, 2013, Posted by , In Presentations, By ,, , With Comments Off on Presentation: Knowledge management for transmembrane transporters

Managing Knowledge about Tissues, Brussels, Belgium Daniela Digles (University of Vienna) View presentation

Conference: ISWC 2013

On October 25, 2013, Posted by , In Conferences, By ,,,,,,,,, , With Comments Off on Conference: ISWC 2013

ISWC 2013, The 12th International Semantic Web Conference, Sydney, Australia Paul Groth (VU University Amsterdam) and Carole Goble (University of Manchester) submitted a paper: Incorporating private and commercial data into an open linked data platform for drug discovery Alasdair Gray (Heriot-Watt University) gave a presentation for the ISWC 2013 Semantic Web…

Presentation: Incorporating Commercial and Private Data into an Open Linked Data Platform for Drug Discovery

On October 25, 2013, Posted by , In Presentations, By ,,, , With Comments Off on Presentation: Incorporating Commercial and Private Data into an Open Linked Data Platform for Drug Discovery

ISWC 2013, The 12th International Semantic Web Conference, Sydney, Australia Alasdair Gray (Heriot-Watt University) View presentation

Open PHACTS welcomes Heriot-Watt as an Associated Partner

On October 24, 2013, Posted by , In News, By ,, , With Comments Off on Open PHACTS welcomes Heriot-Watt as an Associated Partner

Open PHACTS extends a warm welcome to our new Associated Partner Heriot-Watt University. A full list of Associated Partners can be found here. Find out more about how you can get involved with Open PHACTS!

Open PHACTS: The Future

On October 23, 2013, Posted by , In News, By , With Comments Off on Open PHACTS: The Future

Take a look at these slides to see what is next in Open PHACTS and how you can get involved: The Future of Open PHACTS

Publication: Incorporating private and commercial data into an open linked data platform for drug discovery

On October 22, 2013, Posted by , In Publications, By ,,,,,,,,,,,,,, , With Comments Off on Publication: Incorporating private and commercial data into an open linked data platform for drug discovery

The Open PHACTS Discovery Platform aims to provide an integrated information space to advance pharmacological research in the area of drug discovery. Effective drug discovery requires comprehensive data coverage, i.e. integrating all available sources of pharmacology data. While many relevant data sources are available on the linked open data cloud,…

Publication: Including Co-referent URIs in a SPARQL Query

On October 22, 2013, Posted by , In Publications, With Comments Off on Publication: Including Co-referent URIs in a SPARQL Query

Linked data relies on instance level links between potentially differing representations of concepts in multiple datasets. However, in large complex domains, such as pharmacology, the inter-relationship of data instances needs to consider the context (e.g. task, role) of the user and the assumptions they want to apply to the data….

Conference: COLD 2013

COLD 2013, Fourth International Workshop on Consuming Linked Data, Sydney, Australia Alasdair Gray (Heriot-Watt University) gave a presentation: Including Co-referent URIs in a SPARQL Query, and a full paper with the same title was submitted