Webinar: Computational Protocols for in silico Target Validation
On April 25, 2016,
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In Webinars, By janssen,Edgar Jacoby,phenotypic screening,webinar , With Comments Off on Webinar: Computational Protocols for in silico Target Validation
Edgar Jacoby (Janssen) discusses computational protocols for in silico target validation, and “knowing the knowns” in phenotypic screening. Watch webinar video | View webinar slides
Webinar: Target Validation Protocols
On April 12, 2016,
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In News, By janssen,Edgar Jacoby,developer news,researcher news,foundation news,webinar,science and open phacts , With Comments Off on Webinar: Target Validation Protocols
Now that the Open PHACTS project is complete, we’re opening our regular discussions about using Open PHACTS for science up to the whole community, with a series of free monthly webinars. Our next webinar will be about how the Open PHACTS Discovery Platform can be used for in silico target validation….
Linking Life Science Data: Design to Implementation, and Beyond
On February 19, 2016,
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In Community Workshops,Conferences,Project Meetings, By alasdair gray,astrazeneca,heriot-watt,maastricht,glaxosmithkline,bryn williams-jones,gerhard ecker,vienna,european bioinformatics institute,ebi,lee harland,imi,daniela digles,barend mons,lumc,paul groth,herman van vlijmen,janssen,openlink,carole goble,stefan senger,nick lynch,ryan miller,eli lilly,lilly,nuria queralt-rosinach,ferran sanz,manchester,barbara zdrazil,Edgar Jacoby,Jean-Marc Neefs,efpia,ann martin,foundation news,scibite,psmar,elsevier,george papadatos,embl-ebi,nuria queralt,luca bartek,derek marren,emily jamieson,tareq malas,lewis mervin,joseph mullen,pierre meulien,innovative medicines initiative,innomeds,theo meert,hugh williams,strathclyde,jana gurinova,glasgow,cambridge,newcastle upon tyne,jeremy yang,indiana,dean allemang,working ontologist , With Comments Off on Linking Life Science Data: Design to Implementation, and Beyond
Open PHACTS project closing conference (Vienna, Austria)
Poster: Assessing multi target SAR by using pharmacological and pathway data from the public domain
On July 23, 2015,
Posted by anika ,
In Posters, By gerhard ecker,daniela digles,stefan senger,barbara zdrazil,Edgar Jacoby,gordon,gordon research conference , With Comments Off on Poster: Assessing multi target SAR by using pharmacological and pathway data from the public domain
Gordon Research Conference on Computer Aided Drug Design, West Dover, USA View poster
Open PHACTS Phenotypic Screening Workshop
On February 17, 2015,
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In Community Workshops, By astrazeneca,merck,glaxosmithkline,bryn williams-jones,janssen,ola engkvist,eli lilly,david wild,Edgar Jacoby,phenotypic screening,victor segarra,arsenio nueda,maria jesus blanco,marta pineiro-nunez,almirall,javier burgueno,jose miguel vela,esteve,ceara rea,petr bartunek,eu-openscreen,ivan comella,martin daffertshofer,perkinelmer,data2discovery,openscreen , With Comments Off on Open PHACTS Phenotypic Screening Workshop
Understanding the knowledge management needs of phenotypic screening (Santiago de Compostela, Spain)
Publication: The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research
On December 18, 2014,
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In Publications, By ronald siebes,gerhard ecker,chris evelo,christine chichester,daniela digles,andra waagmeester,stefan senger,barbara zdrazil,Edgar Jacoby,Emiliano Cuadrado Rodríguez,plos one,Lars Richter,Joseline Ratnam,Jean-Marc Neefs,Hannah Tipney,Glyn Bradley,Chau Han Chau,Jose Brea,Maria Isabel Loza,plos , With Comments Off on Publication: The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research
Integration of open access, curated, high-quality information from multiple disciplines in the Life and Biomedical Sciences provides a holistic understanding of the domain. Additionally, the effective linking of diverse data sources can unearth hidden relationships and guide potential research strategies. However, given the lack of consistency between descriptors and identifiers…
Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS
On December 3, 2013,
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In Publications, By gerhard ecker,antony williams,lee harland,christine chichester,stefan senger,matthias rarey,niklas blomberg,olivier taboureau,barbara zdrazil,jordi mestres,Marta Pinto,Kamal Azzaoui,Edgar Jacoby,Emiliano Cuadrado Rodríguez,Mabel Loza,Victor de la Torre,computational chemogenomics , With Comments Off on Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS
This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity…
Publication: Scientific competency questions as the basis for semantically enriched open pharmacological space development
On May 20, 2013,
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In Publications, By bryn williams-jones,gerhard ecker,antony williams,lee harland,christine chichester,steve pettifer,stefan senger,matthias rarey,manuel pastor,niklas blomberg,olivier taboureau,drug discovery today,barbara zdrazil,jordi mestres,Marta Pinto,Kamal Azzaoui,Edgar Jacoby,Emiliano Cuadrado Rodríguez,Mabel Loza,Victor de la Torre , With Comments Off on Publication: Scientific competency questions as the basis for semantically enriched open pharmacological space development
Molecular information systems play an important part in modern data-driven drug discovery. They do not only support decision making but also enable new discoveries via association and inference. In this review, we outline the scientific requirements identified by the Innovative Medicines Initiative (IMI) Open PHACTS consortium for the design of…