Publication: The FAIR Guiding Principles for scientific data management and stewardship

There is an urgent need to improve the infrastructure supporting the reuse of scholarly data. A diverse set of stakeholders—representing academia, industry, funding agencies, and scholarly publishers—have come together to design and jointly endorse a concise and measureable set of principles that we refer to as the FAIR Data Principles….

Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS

On December 3, 2013, Posted by , In Publications, By ,,,,,,,,,,,,,,,, , With Comments Off on Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS

This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity…

Publication: Scientific competency questions as the basis for semantically enriched open pharmacological space development

Molecular information systems play an important part in modern data-driven drug discovery. They do not only support decision making but also enable new discoveries via association and inference. In this review, we outline the scientific requirements identified by the Innovative Medicines Initiative (IMI) Open PHACTS consortium for the design of…

Conference: 19th EuroQSAR 2012

19th EuroQSAR, Knowledge Enabled Ligand Design, Vienna, Austria Open PHACTS hosted a community workshop: Introducing Open PHACTS Mark Forster gave a presentation: Open Innovation Applied to Agrochemical Discovery Steve Pettifer gave a presentation: Utopia Documents Lee Harland gave a presentation: Open Drug Discovery Intelligence: Open PHACTS and SciBite Niklas Blomberg gave a…

Publication: Molecular Informatics Special Issue: Open Innovation in Drug Discovery

Several publications about Open PHACTS were included in this Special Issue of Molecular Informatics. Open Innovation in Drug Discovery. Gerhard F. Ecker, Bryn Williams-Jones; Molecular Informatics 31: 519–520 Taking Open Innovation to the Molecular Level – Strengths and Limitations. Barbara Zdrazil, Niklas Blomberg, Gerhard F. Ecker; Molecular Informatics 31: 528–535 PharmaTrek: A Semantic Web Explorer for Open Innovation in Multitarget…

Publication: Open PHACTS: Semantic interoperability for drug discovery

On June 6, 2012, Posted by , In Publications, By ,,,,,,,,,,, , With Comments Off on Publication: Open PHACTS: Semantic interoperability for drug discovery

Open PHACTS is a public–private partnership between academia, publishers, small and medium sized enterprises and pharmaceutical companies. The goal of the project is to deliver and sustain an ‘open pharmacological space’ using and enhancing state-of-the-art semantic web standards and technologies. It is focused on practical and robust applications to solve…

Press Release: Semantic ‘lego’: an information framework to drive drug discovery

On May 27, 2011, Posted by , In Press Releases, By ,,,,,,, , With Comments Off on Press Release: Semantic ‘lego’: an information framework to drive drug discovery

(PDF) Vienna, Austria – A new consortium of European organisations unite to support next generation drug discovery by providing a single view across data sources, bringing the semantic web to drug discovery. The Open PHACTS consortium, funded by the Innovative Medicines Initiative, will reduce the barriers to drug discovery by applying semantic…

Publication: Knowledge Driven Drug Discovery goes Semantic

On April 18, 2011, Posted by , In Publications, By ,,,,,, , With Comments Off on Publication: Knowledge Driven Drug Discovery goes Semantic

While the availability of freely accessible information sources relevant to medicinal chemistry and drug discovery has grown over the past few years, the knowledge management challenges of this data have also grown enormously: how to get consistent answers, how to manage different interfaces, how to judge data quality, and how…