Publication: Using the BioAssy Ontology for Analyzing High-Throughput Screening Data

On December 15, 2014, Posted by , In Publications, By ,,,,,,, , With Comments Off on Publication: Using the BioAssy Ontology for Analyzing High-Throughput Screening Data

High-throughput screening (HTS) is the main starting point for hit identification in drug discovery programs. This has led to a rapid increase of available screening data both within pharmaceutical companies and the public domain. We have used the BioAssay Ontology (BAO) 2.0 for assay annotation within AstraZeneca to enable comparison…

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Open PHACTS poster wins prize at CSHALS 2014 in Boston

On April 17, 2014, Posted by , In News, By ,,,,,, , With Comments Off on Open PHACTS poster wins prize at CSHALS 2014 in Boston

Simon Rakov, Linda Zander Balderud and Tom Plasterer from AstraZeneca presented a poster entitled “BAO Reveal: Assay Analysis Using the BioAssay Ontology and Open PHACTS” at the Conference on Semantics in Healthcare and Life Sciences (CSHALS) 2014 in Boston. The poster won the F1000 (Faculty of 1000) Poster Prize, and…

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Publication: Transporter assays and assay ontologies: useful tools for drug discovery

On April 5, 2014, Posted by , In Publications, By ,,,,,, , With Comments Off on Publication: Transporter assays and assay ontologies: useful tools for drug discovery

Transport proteins represent an eminent class of drug targets and ADMET (absorption, distribution, metabolism, excretion, toxicity) associated genes. There exists a large number of distinct activity assays for transport proteins, depending on not only the measurement needed (e.g. transport activity, strength of ligand–protein interaction), but also due to heterogeneous assay…

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Poster: BAO Reveal: Assay Analysis Using the BioAssay Ontology and Open PHACTS

On February 28, 2014, Posted by , In Posters, By ,,,,,, , With Comments Off on Poster: BAO Reveal: Assay Analysis Using the BioAssay Ontology and Open PHACTS

CSHALS, Conference on Semantics in Healthcare and Life Sciences, Boston, USA Awarded Faculty of 1000 Poster Prize View poster

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Conference: 5th Annual aDREAM Conference

On January 8, 2014, Posted by , In Conferences, By ,,,, , With Comments Off on Conference: 5th Annual aDREAM Conference

5th Development of Robust Experimental Assay Methods (aDREAM) Conference, Madison, USA Linda Zander-Balderud (AstraZeneca) gave a presentation: Applying BioAssay Ontology to facilitate HTS analysis

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Presentation: Applying BioAssay Ontology to facilitate HTS analysis

On January 8, 2014, Posted by , In Presentations, By ,,,, , With Comments Off on Presentation: Applying BioAssay Ontology to facilitate HTS analysis

5th Development of Robust Experimental Assay Methods (aDREAM) Conference, Madison, USA Linda Zander-Balderud (AstraZeneca) View presentation

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Publication: Molecular Informatics Special Issue: Open Innovation in Drug Discovery

On August 15, 2012, Posted by , In Publications, By ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, , With Comments Off on Publication: Molecular Informatics Special Issue: Open Innovation in Drug Discovery

Several publications about Open PHACTS were included in this Special Issue of Molecular Informatics. Open Innovation in Drug Discovery. Gerhard F. Ecker, Bryn Williams-Jones; Molecular Informatics 31: 519–520 Taking Open Innovation to the Molecular Level – Strengths and Limitations. Barbara Zdrazil, Niklas Blomberg, Gerhard F. Ecker; Molecular Informatics 31: 528–535 PharmaTrek: A Semantic Web Explorer for Open Innovation in Multitarget…

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