Poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

On March 20, 2014, Posted by , In Posters, By ,,,,,,,, , With Comments Off on Poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

247th ACS National Meeting & Exposition, Dallas, USA View poster

Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS

On December 3, 2013, Posted by , In Publications, By ,,,,,,,,,,,,,,,, , With Comments Off on Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS

This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity…

Poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

On November 12, 2013, Posted by , In Posters, By ,,,,,,,, , With Comments Off on Poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

9th German Conference on Chemoinformatics, Fulda, Germany Katrin Stierand (University of Hamburg) View poster

Publication: Scientific competency questions as the basis for semantically enriched open pharmacological space development

Molecular information systems play an important part in modern data-driven drug discovery. They do not only support decision making but also enable new discoveries via association and inference. In this review, we outline the scientific requirements identified by the Innovative Medicines Initiative (IMI) Open PHACTS consortium for the design of…

Publication: Molecular Informatics Special Issue: Open Innovation in Drug Discovery

Several publications about Open PHACTS were included in this Special Issue of Molecular Informatics. Open Innovation in Drug Discovery. Gerhard F. Ecker, Bryn Williams-Jones; Molecular Informatics 31: 519–520 Taking Open Innovation to the Molecular Level – Strengths and Limitations. Barbara Zdrazil, Niklas Blomberg, Gerhard F. Ecker; Molecular Informatics 31: 528–535 PharmaTrek: A Semantic Web Explorer for Open Innovation in Multitarget…