Presentation: Collaboration and true sharing
Big Data Analytics in Pharma, Brussels, Belgium Derek Marren (Eli Lilly) View presentation
Presentation: Too Much Data or Too Little Cooperation?
Big Data in Pharma USA 2015, Boston, USA Tom Plasterer (AstraZeneca) View presentation
Presentation: Data Integration in a Big Data Context
Ambient Assisted Living (AAL) Forum 2015, Ghent, Belgium Alasdair Gray (Heriot-Watt University) View presentation
Presentation: An Open PHACTS KNIME workflow to collect compound data from public databases
24th Scientific Congress of the Austrian Pharmaceutical Society (OePhG), Vienna, Austria Daniela Digles (University of Vienna) View presentation
Presentation: Open, reusable graph annotations
BioHackathon 2015 Symbosium, Nagasaki, Japan Mark Thompson (Leiden University Medical Centre) View presentation
Presentation: The DisGeNET Discovery Platform
BioHackathon 2015 Symposium, Nagasaki, Japan Núria Queralt-Rosinach (IMIM) View presentation
Poster: Discriminating P-gp from BCRP inhibitory activity by multi-class classification models
8th SFB35 Symposium 2015, Vienna, Austria View poster
Presentation: SureChEMBL: An open patent chemistry resource
250th ACS National Meeting & Exposition, Boston, USA George Papadatos (EMBL-EBI) View presentation
Presentation: Topliss batchwise scheme reviewed in the era of Open Data
250th ACS National Meeting & Exposition, Boston, USA Gerhard Ecker (University of Vienna) View presentation
Presentation: Workflow-based data integration for drug discovery
250th ACS National Meeting & Exposition, Boston, USA Richard Kidd (Royal Society of Chemistry) View presentation
Publication: Medicinal chemistry in the era of big data
In the era of big data medicinal chemists are exposed to an enormous amount of bioactivity data. Numerous public data sources allow for querying across medium to large data sets mostly compiled from literature. However, the data available are still quite incomplete and of mixed quality. This mini review will…
Presentation: Visualising Open PHACTS linked data with widgets
Bioinformatics Open Source Conference (BOSC) 2015, Dublin, Ireland Ian Dunlop (University of Manchester) Watch presentation video | View presentation slides
Publication: The Chemical Validation and Standardization Platform (CVSP): large-scale automated validation of chemical structure datasets
There are presently hundreds of online databases hosting millions of chemical compounds and associated data. As a result of the number of cheminformatics software tools that can be used to produce the data, subtle differences between the various cheminformatics platforms, as well as the naivety of the software users, there…
Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences
Swedish Linked Data Network Meet-up, Gothenburg, Sweden Ola Engkvist (AstraZeneca) Watch presentation video | View presentation slides
Poster: Biological Interactions Types for WikiPathways
HARMONY 2015, Wittenberg, Germany View poster
Presentation: The Open PHACTS Foundation: building open semantic data services for life sciences
Bio-IT World Conference & Expo 2015, Boston, USA Bryn Williams-Jones (Open PHACTS Foundation) View presentation
Presentation: The Open PHACTS Discovery Platform – Collaborations in Semantic Data Integration for Life Sciences
Pistoia Alliance Spring Conference 2015, Dübendorf, Switzerland Nick Lynch (Open PHACTS Foundation) View presentation
Publication: Publishing DisGeNET as Nanopublications
The increasing and unprecedented publication rate in the biomedical field is a major bottleneck for discovery in Life Sciences. Although the scientific community is limited an inability to manually curate facts from published papers, recent approaches enable the automatic, scalable and reliable extraction of assertions from the scientific literature. While…
Poster: Drug Discovery FAQ: Open PHACTS API and KNIME have the answers!
8th KNIME User Group Meeting and Workshops, Berlin, Germany View poster
Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences
57th NFAIS Annual Conference, Crystal City, USA Tim Clark (Scientific Advisory Board) View presentation
Publication: Extraction of relations between genes and diseases from text and large-scale data analysis: implications for translational research
Background Current biomedical research needs to leverage and exploit the large amount of information reported in scientific publications. Automated text mining approaches, in particular those aimed at finding relationships between entities, are key for identification of actionable knowledge from free text repositories. We present the BeFree system aimed at identifying…
Presentation: What is Open PHACTS and why would you care?
CiMUS Innopharma Open Innovation Day, Santiago de Compostela, Spain Stefan Senger (GlaxoSmithKline) View presentation
Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences
SLAS 2015, 4th Annual Conference & Exhibition, Washington, D.C., USA Bryn Williams-Jones (Open PHACTS Foundation) View presentation
Publication: Using the BioAssy Ontology for Analyzing High-Throughput Screening Data
High-throughput screening (HTS) is the main starting point for hit identification in drug discovery programs. This has led to a rapid increase of available screening data both within pharmaceutical companies and the public domain. We have used the BioAssay Ontology (BAO) 2.0 for assay annotation within AstraZeneca to enable comparison…
Presentation: The Open PHACTS Discovery Platform: Semantic Data Integration for Life Sciences
6th Spanish Drug Discovery Network (SDDN) Meeting, Madrid, Spain Bryn Williams-Jones (Connected Discovery) View presentation
Publication: Drug Discovery FAQs: Workflows for answering cross concept drug discovery questions
Modern data-driven drug discovery requires integrated resources to support decision-making and enable new discoveries. The Open PHACTS Discovery Platform (http://dev.openphacts.org) was built to address this requirement by focusing on drug discovery questions that are of high priority to the pharmaceutical industry. Although complex, most of these frequently asked questions (FAQs)…
Publication: On the formulation of performant SPARQL queries
The combination of the flexibility of RDF and the expressiveness of SPARQL provides a powerful mechanism to model, integrate and query data. However, these properties also mean that it is nontrivial to write performant SPARQL queries. Indeed, it is quite easy to create queries that tax even the most optimised…