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Presentation: Collaboration and true sharing

Big Data Analytics in Pharma, Brussels, Belgium Derek Marren (Eli Lilly) View presentation

Presentation: Too Much Data or Too Little Cooperation?

Big Data in Pharma USA 2015, Boston, USA Tom Plasterer (AstraZeneca) View presentation

Presentation: Data Integration in a Big Data Context

Ambient Assisted Living (AAL) Forum 2015, Ghent, Belgium Alasdair Gray (Heriot-Watt University) View presentation

Presentation: An Open PHACTS KNIME workflow to collect compound data from public databases

24th Scientific Congress of the Austrian Pharmaceutical Society (OePhG), Vienna, Austria Daniela Digles (University of Vienna) View presentation

Presentation: Open, reusable graph annotations

BioHackathon 2015 Symbosium, Nagasaki, Japan Mark Thompson (Leiden University Medical Centre) View presentation  

Presentation: The DisGeNET Discovery Platform

BioHackathon 2015 Symposium, Nagasaki, Japan Núria Queralt-Rosinach (IMIM) View presentation

Poster: Discriminating P-gp from BCRP inhibitory activity by multi-class classification models

On September 9, 2015, Posted by , In Posters, By ,, , With No Comments

8th SFB35 Symposium 2015, Vienna, Austria View poster

Presentation: SureChEMBL: An open patent chemistry resource

On August 20, 2015, Posted by , In Presentations, With No Comments

250th ACS National Meeting & Exposition, Boston, USA George Papadatos (EMBL-EBI) View presentation

Presentation: Topliss batchwise scheme reviewed in the era of Open Data

On August 20, 2015, Posted by , In Presentations, By ,,, , With No Comments

250th ACS National Meeting & Exposition, Boston, USA Gerhard Ecker (University of Vienna) View presentation

Presentation: Workflow-based data integration for drug discovery

250th ACS National Meeting & Exposition, Boston, USA Richard Kidd (Royal Society of Chemistry) View presentation

Poster: Assessing multi target SAR by using pharmacological and pathway data from the public domain

Gordon Research Conference on Computer Aided Drug Design, West Dover, USA View poster

Publication: Medicinal chemistry in the era of big data

In the era of big data medicinal chemists are exposed to an enormous amount of bioactivity data. Numerous public data sources allow for querying across medium to large data sets mostly compiled from literature. However, the data available are still quite incomplete and of mixed quality. This mini review will…

Presentation: Visualising Open PHACTS linked data with widgets

On July 11, 2015, Posted by , In Presentations, By ,,,, , With No Comments

Bioinformatics Open Source Conference (BOSC) 2015, Dublin, Ireland Ian Dunlop (University of Manchester) Watch presentation video | View presentation slides

Publication: The Chemical Validation and Standardization Platform (CVSP): large-scale automated validation of chemical structure datasets

There are presently hundreds of online databases hosting millions of chemical compounds and associated data. As a result of the number of cheminformatics software tools that can be used to produce the data, subtle differences between the various cheminformatics platforms, as well as the naivety of the software users, there…

Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences

Swedish Linked Data Network Meet-up, Gothenburg, Sweden Ola Engkvist (AstraZeneca) Watch presentation video | View presentation slides

Poster: Biological Interactions Types for WikiPathways

HARMONY 2015, Wittenberg, Germany View poster

Presentation: The Open PHACTS Foundation: building open semantic data services for life sciences

Bio-IT World Conference & Expo 2015, Boston, USA Bryn Williams-Jones (Open PHACTS Foundation) View presentation

Publication: DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes

DisGeNET is a comprehensive discovery platform designed to address a variety of questions concerning the genetic underpinning of human diseases. DisGeNET contains over 380 000 associations between >16 000 genes and 13 000 diseases, which makes it one of the largest repositories currently available of its kind. DisGeNET integrates expert-curated databases with…

Presentation: The Open PHACTS Discovery Platform – Collaborations in Semantic Data Integration for Life Sciences

Pistoia Alliance Spring Conference 2015, Dübendorf, Switzerland Nick Lynch (Open PHACTS Foundation) View presentation

Publication: Publishing DisGeNET as Nanopublications

The increasing and unprecedented publication rate in the biomedical field is a major bottleneck for discovery in Life Sciences. Although the scientific community is limited an inability to manually curate facts from published papers, recent approaches enable the automatic, scalable and reliable extraction of assertions from the scientific literature. While…

Poster: Drug Discovery FAQ: Open PHACTS API and KNIME have the answers!

8th KNIME User Group Meeting and Workshops, Berlin, Germany View poster

Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences

57th NFAIS Annual Conference, Crystal City, USA Tim Clark (Scientific Advisory Board) View presentation  

Publication: Extraction of relations between genes and diseases from text and large-scale data analysis: implications for translational research

Background Current biomedical research needs to leverage and exploit the large amount of information reported in scientific publications. Automated text mining approaches, in particular those aimed at finding relationships between entities, are key for identification of actionable knowledge from free text repositories. We present the BeFree system aimed at identifying…

Presentation: What is Open PHACTS and why would you care?

CiMUS Innopharma Open Innovation Day, Santiago de Compostela, Spain Stefan Senger (GlaxoSmithKline) View presentation

Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences

On February 10, 2015, Posted by , In Presentations, By ,,, , With No Comments

SLAS 2015, 4th Annual Conference & Exhibition, Washington, D.C., USA Bryn Williams-Jones (Open PHACTS Foundation) View presentation

Publication: The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research

Integration of open access, curated, high-quality information from multiple disciplines in the Life and Biomedical Sciences provides a holistic understanding of the domain. Additionally, the effective linking of diverse data sources can unearth hidden relationships and guide potential research strategies. However, given the lack of consistency between descriptors and identifiers…

Publication: Using the BioAssy Ontology for Analyzing High-Throughput Screening Data

High-throughput screening (HTS) is the main starting point for hit identification in drug discovery programs. This has led to a rapid increase of available screening data both within pharmaceutical companies and the public domain. We have used the BioAssay Ontology (BAO) 2.0 for assay annotation within AstraZeneca to enable comparison…

Presentation: The Open PHACTS Discovery Platform: Semantic Data Integration for Life Sciences

6th Spanish Drug Discovery Network (SDDN) Meeting, Madrid, Spain Bryn Williams-Jones (Connected Discovery) View presentation

Publication: Drug Discovery FAQs: Workflows for answering cross concept drug discovery questions

On November 20, 2014, Posted by , In Publications, With No Comments

Modern data-driven drug discovery requires integrated resources to support decision-making and enable new discoveries. The Open PHACTS Discovery Platform (http://dev.openphacts.org) was built to address this requirement by focusing on drug discovery questions that are of high priority to the pharmaceutical industry. Although complex, most of these frequently asked questions (FAQs)…

Publication: On the formulation of performant SPARQL queries

The combination of the flexibility of RDF and the expressiveness of SPARQL provides a powerful mechanism to model, integrate and query data. However, these properties also mean that it is nontrivial to write performant SPARQL queries. Indeed, it is quite easy to create queries that tax even the most optimised…