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Presentation: The Open PHACTS Discovery Platform

SICSA DEMOfest 2014, Edinburgh, UK Alasdair Gray (Heriot-Watt University) View presentation

Presentation: Help me describe my data: A demonstration of the Open PHACTS VoID Editor

On October 20, 2014, Posted by , In Presentations, By ,,, , With No Comments

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy Alasdair Gray (Heriot-Watt University) View presentation | Paper

Presentation: Capturing Provenance for a Linkset of Convenience

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy Simon Jupp (European Bioinformatics Institute) View presentation

Presentation: Scientific Lenses to Support Multiple Views over Linked Chemistry Data

On October 20, 2014, Posted by , In Presentations, By ,,, , With No Comments

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy Alasdair Gray (Heriot-Watt University) View presentation See also: Full publication: Scientific Lenses to Support Multiple Views over Linked Chemistry Data

Presentation: The Knowledge-Remixing Bottleneck – Hidden Decisions

On October 19, 2014, Posted by , In Presentations, By ,,,, , With No Comments

Workshop on Context, Interpretation and Meaning, held at the International Semantic Web Conference (ISWC) 2014 at Riva del Garda, Trentino, Italy Paul Groth (VU University Amsterdam) View presentation

Presentation: A Justification-based Semantic Framework for Representing, Evaluating and Utilizing Terminology Mappings

On October 19, 2014, Posted by , In Presentations, By ,,, , With No Comments

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy Kerstin Forsberg (AstraZeneca) View presentation

Publication: Scientific Lenses to Support Multiple Views over Linked Chemistry Data

When are two entries about a small molecule in different datasets the same? If they have the same drug name, chemical structure, or some other criteria? The choice depends upon the application to which the data will be put. However, existing Linked Data approaches provide a single global view over…

Poster: DisGeNET: a discovery platform for the exploration of human diseases and their genes

XII Symposium on Bioinformatics, Sevilla, Italy View poster

Presentation: The Open PHArmacological Concepts Triple Store: Solutions and the Foundation

OpenTox Euro 2014, Athens, Greece Egon Willighagen (Maastricht University) View presentation | Overview

Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration of Medicinal Chemists

EFMC-ISMC 2014, XXIII International Symposium on Medicinal Chemistry, Lisbon, Portugal Gerhard Ecker (University of Vienna) View presentation

Presentation: Open PHACTS – The use of open data for in silico models

On September 4, 2014, Posted by , In Presentations, By ,,, , With No Comments

20th EuroQSAR, Understanding Chemical-Biological Interactions, St Petersburg, Russia Gerhard Ecker (University of Vienna) View presentation

Presentation: Open innovation contributions from RSC resulting from the Open Phacts project

248th ACS National Meeting & Exposition, San Francisco, USA Antony Williams (Royal Society of Chemistry) View presentation

Presentation: Open PHACTS: Linked Open Data for Drug Discovery

PiLOD Meeting, Hilversum, the Netherlands Herman van Vlijmen (Janssen), Orri Erling (OpenLink Software) View presentation

Presentation: Provenance: An Introduction to PROV

5th International Provenance and Annotation Workshop, Cologne, Germany Paul Groth (Vrije Universitat Amsterdam) View presentation

Publication: Querying neXtProt nanopublications and their value for insights on sequence variants and tissue expression

Understanding how genetic differences between individuals impact the regulation, expression, and ultimately function of proteins is an important step toward realizing the promise of personal medicine. There are several technical barriers hindering the transition of biological knowledge into the applications relevant to precision medicine. One important challenge for data integration…

Poster: Open PHACTS: Solutions and the Foundation

On June 5, 2014, Posted by , In Posters, By ,, , With No Comments

10th ICCS, International Conference on Chemical Structures, Noordwijkerhout, the Netherlands View poster

Presentation: Scientific Lenses over Linked Chemistry Data using BridgeDb and the Open PHACTS Chemistry Registration System

10th ICCS, International Conference on Chemical Structures, Noordwijkerhout, the Netherlands Colin Batchelor (Royal Society of Chemistry) View presentation

Presentation: SureChEMBL – Open Patent Data

10th ICCS, International Conference on Chemical Structures, Noordwijkerhout, the Netherlands Anna Gaulton (European Bioinformatics Institute) View presentation

Presentation: Open PHACTS: Practical Semantics For Drug Discovery

Bio-IT World Conference & Expo 2014, Boston, USA Lee Harland (Connected Discovery) View presentation

Presentation: Data Citation and Linked Open Data – From links to citation?

US National Science Foundation Workshop: Computational Challenges in Data Citation, Philadelphia, USA Paul Groth (VU University Amsterdam) View presentation

Publication: A Knowledge-Driven Approach to Extract Disease-Related Biomarkers from the Literature

The biomedical literature represents a rich source of biomarker information. However, both the size of literature databases and their lack of standardization hamper the automatic exploitation of the information contained in these resources. Text mining approaches have proven to be useful for the exploitation of information contained in the scientific…

Publication: Transporter taxonomy – a comparison of different transport protein classification schemes

Currently, there are more than 800 well characterized human membrane transport proteins (including channels and transporters) and there are estimates that about 10% (approx. 2000) of all human genes are related to transport. Membrane transport proteins are of interest as potential drug targets, for drug delivery, and as a cause…

Publication: Transporter assays and assay ontologies: useful tools for drug discovery

Transport proteins represent an eminent class of drug targets and ADMET (absorption, distribution, metabolism, excretion, toxicity) associated genes. There exists a large number of distinct activity assays for transport proteins, depending on not only the measurement needed (e.g. transport activity, strength of ligand–protein interaction), but also due to heterogeneous assay…

Poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

247th ACS National Meeting & Exposition, Dallas, USA View poster

Presentation: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web

Joint CINF-RSC CICAG Symposium at the 247th ACS National Meeting & Exposition, Dallas, USA Katrin Stierand (University of Hamburg) View presentation

Presentation: A Data Platform for Drug Discovery

European Data Forum 2014, Athens, Greece Paul Groth (VU University Amsterdam) View presentation Watch presentation video

Publication: Exploiting open data: a new era in pharmacoinformatics

Within the last decade open data concepts has been gaining increasing interest in the area of drug discovery. With the launch of ChEMBL and PubChem, an enormous amount of bioactivity data was made easily accessible to the public domain. In addition, platforms that semantically integrate those data, such as the…

Poster: Answering drug-discovery research questions with Open PHACTS and KNIME

On February 28, 2014, Posted by , In Posters, By ,, , With No Comments

47th Scientific training event for pharmacists,Schladming, Austria View poster

Poster: BAO Reveal: Assay Analysis Using the BioAssay Ontology and Open PHACTS

CSHALS, Conference on Semantics in Healthcare and Life Sciences, Boston, USA Awarded Faculty of 1000 Poster Prize View poster

Presentation: Semantics Based Biomedical Knowledge Search

On February 28, 2014, Posted by , In Presentations, By ,,, , With No Comments

CSHALS, Conference on Semantics in Healthcare and Life Sciences, Boston, USA Barend Mons (Leiden University Medical Centre) View presentation