Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences

On April 28, 2015, Posted by , In Presentations, By ,,,, , With Comments Off on Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences

Swedish Linked Data Network Meet-up, Gothenburg, Sweden Ola Engkvist (AstraZeneca) Watch presentation video | View presentation slides

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Conference: Swedish Linked Data Network Meet-up

On April 28, 2015, Posted by , In Conferences, By ,,, , With Comments Off on Conference: Swedish Linked Data Network Meet-up

Swedish Linked Data Network Meet-up, Gothenburg, Sweden Ola Engkvist (AstraZeneca) gave a presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences

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Open PHACTS Phenotypic Screening Workshop

On February 17, 2015, Posted by , In Community Workshops, By ,,,,,,,,,,,,,,,,,,,,,,,,, , With Comments Off on Open PHACTS Phenotypic Screening Workshop

Understanding the knowledge management needs of phenotypic screening (Santiago de Compostela, Spain)

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Publication: Using the BioAssy Ontology for Analyzing High-Throughput Screening Data

On December 15, 2014, Posted by , In Publications, By ,,,,,,, , With Comments Off on Publication: Using the BioAssy Ontology for Analyzing High-Throughput Screening Data

High-throughput screening (HTS) is the main starting point for hit identification in drug discovery programs. This has led to a rapid increase of available screening data both within pharmaceutical companies and the public domain. We have used the BioAssay Ontology (BAO) 2.0 for assay annotation within AstraZeneca to enable comparison…

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Publication: Transporter assays and assay ontologies: useful tools for drug discovery

On April 5, 2014, Posted by , In Publications, By ,,,,,, , With Comments Off on Publication: Transporter assays and assay ontologies: useful tools for drug discovery

Transport proteins represent an eminent class of drug targets and ADMET (absorption, distribution, metabolism, excretion, toxicity) associated genes. There exists a large number of distinct activity assays for transport proteins, depending on not only the measurement needed (e.g. transport activity, strength of ligand–protein interaction), but also due to heterogeneous assay…

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Publication: Molecular Informatics Special Issue: Open Innovation in Drug Discovery

On August 15, 2012, Posted by , In Publications, By ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, , With Comments Off on Publication: Molecular Informatics Special Issue: Open Innovation in Drug Discovery

Several publications about Open PHACTS were included in this Special Issue of Molecular Informatics. Open Innovation in Drug Discovery. Gerhard F. Ecker, Bryn Williams-Jones; Molecular Informatics 31: 519–520 Taking Open Innovation to the Molecular Level – Strengths and Limitations. Barbara Zdrazil, Niklas Blomberg, Gerhard F. Ecker; Molecular Informatics 31: 528–535 PharmaTrek: A Semantic Web Explorer for Open Innovation in Multitarget…

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