Presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences

Swedish Linked Data Network Meet-up, Gothenburg, Sweden Ola Engkvist (AstraZeneca) Watch presentation video | View presentation slides

Conference: Swedish Linked Data Network Meet-up

Swedish Linked Data Network Meet-up, Gothenburg, Sweden Ola Engkvist (AstraZeneca) gave a presentation: The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences

Open PHACTS Phenotypic Screening Workshop

Understanding the knowledge management needs of phenotypic screening (Santiago de Compostela, Spain)

Publication: Using the BioAssy Ontology for Analyzing High-Throughput Screening Data

High-throughput screening (HTS) is the main starting point for hit identification in drug discovery programs. This has led to a rapid increase of available screening data both within pharmaceutical companies and the public domain. We have used the BioAssay Ontology (BAO) 2.0 for assay annotation within AstraZeneca to enable comparison…

Publication: Transporter assays and assay ontologies: useful tools for drug discovery

Transport proteins represent an eminent class of drug targets and ADMET (absorption, distribution, metabolism, excretion, toxicity) associated genes. There exists a large number of distinct activity assays for transport proteins, depending on not only the measurement needed (e.g. transport activity, strength of ligand–protein interaction), but also due to heterogeneous assay…

Publication: Molecular Informatics Special Issue: Open Innovation in Drug Discovery

Several publications about Open PHACTS were included in this Special Issue of Molecular Informatics. Open Innovation in Drug Discovery. Gerhard F. Ecker, Bryn Williams-Jones; Molecular Informatics 31: 519–520 Taking Open Innovation to the Molecular Level – Strengths and Limitations. Barbara Zdrazil, Niklas Blomberg, Gerhard F. Ecker; Molecular Informatics 31: 528–535 PharmaTrek: A Semantic Web Explorer for Open Innovation in Multitarget…