In the era of big data medicinal chemists are exposed to an enormous amount of bioactivity data. Numerous public data sources allow for querying across medium to large data sets mostly compiled from literature. However, the data available are still quite incomplete and of mixed quality. This mini review will focus on how medicinal chemists might use such resources and how valuable the current data sources are for guiding drug discovery.

Lars Richter, Gerhard F. Ecker

Full publication: Drug Discovery Today, Volume 14, July 2015, Pages 37–41