Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS
On December 3, 2013,
Posted by wordpressadmin ,
In Publications, By gerhard ecker,antony williams,lee harland,christine chichester,stefan senger,matthias rarey,niklas blomberg,olivier taboureau,barbara zdrazil,jordi mestres,Marta Pinto,Kamal Azzaoui,Edgar Jacoby,Emiliano Cuadrado RodrÃguez,Mabel Loza,Victor de la Torre,computational chemogenomics , With Comments Off on Publication: Scientific requirements for the next generation semantic web-based chemogenomics and systems chemical biology molecular information system OPS
This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity…
Publication: Scientific competency questions as the basis for semantically enriched open pharmacological space development
On May 20, 2013,
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In Publications, By bryn williams-jones,gerhard ecker,antony williams,lee harland,christine chichester,steve pettifer,stefan senger,matthias rarey,manuel pastor,niklas blomberg,olivier taboureau,drug discovery today,barbara zdrazil,jordi mestres,Marta Pinto,Kamal Azzaoui,Edgar Jacoby,Emiliano Cuadrado RodrÃguez,Mabel Loza,Victor de la Torre , With Comments Off on Publication: Scientific competency questions as the basis for semantically enriched open pharmacological space development
Molecular information systems play an important part in modern data-driven drug discovery. They do not only support decision making but also enable new discoveries via association and inference. In this review, we outline the scientific requirements identified by the Innovative Medicines Initiative (IMI) Open PHACTS consortium for the design of…