Poster: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web
247th ACS National Meeting & Exposition, Dallas, USA View poster
Presentation: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web
Joint CINF-RSC CICAG Symposium at the 247th ACS National Meeting & Exposition, Dallas, USA Katrin Stierand (University of Hamburg) View presentation
Presentation: A Data Platform for Drug Discovery
European Data Forum 2014, Athens, Greece Paul Groth (VU University Amsterdam) View presentation Watch presentation video
Conference: CINF-RSC CICAG Symposium
Joint CINF-RSC CICAG Symposium at the 247th ACS National Meeting & Exposition, Dallas, USA Valery Tkachenko (Royal Society of Chemistry) represented Open PHACTS, and Katrin Stierand (University of Hamburg) gave a presentation: Accessing Open PHACTS: Interactive exploration of compounds and targets from the semantic web
2nd Open PHACTS Pipeline Pilot Hackathon held
On 6 March, 2014, the 2nd Open PHACTS Pipeline Pilot Hackathon took place on the Merck campus in Darmstadt, Germany. Attendees from eight different industrial and academic institutions worked on the new version 2.0 of the Open PHACTS component collection which was provided by Accelrys through financial support by Janssen Pharmaceutica….
Open PHACTS endorses Data Citation
The Joint Declaration of Data Citation Principles is the culmination of work by the Data Citation Synthesis Group of Force11, made up of a range of organisations including Creative Commons, the EBI and CERN. Open PHACTS endorses this set of principles which encourages data to be cited as an important part…
Project Meeting: Hackathon
2nd Pipeline Pilot Hackathon (Darmstadt, Germany)
Poster: Answering drug-discovery research questions with Open PHACTS and KNIME
47th Scientific training event for pharmacists,Schladming, Austria View poster
Poster: BAO Reveal: Assay Analysis Using the BioAssay Ontology and Open PHACTS
CSHALS, Conference on Semantics in Healthcare and Life Sciences, Boston, USA Awarded Faculty of 1000 Poster Prize View poster
Presentation: The Open PHACTS project – Progress and Future Sustainability
CSHALS, Conference on Semantics in Healthcare and Life Sciences, Boston, USA Tom Plasterer (AstraZeneca) View presentation
Conference: CSHALS 2014
CSHALS, Conference on Semantics in Healthcare and Life Sciences, Boston, USA Open PHACTS representatives gave several presentations
Utopia Documents integrates with Discovery Platform
Utopia Documents is a free PDF reader that connects the static content of scientific articles to the dynamic world of online content and allows data to be extracted from figures and tables within the scientific literature. Interesting concepts and words can be further investigated using a variety of tools –…
Open PHACTS Explorer updated
The Open PHACTS Explorer now uses version 1.3 of the Open PHACTS API. This includes an update of the pharmacology data (from ChEMBL 13 to ChEMBL 16). Changes with this update: pChEMBL values (a unification over different activity types) are now available. They can be used to sort and filter…
Presentation: Linked Data API (LDA)
EUCLID Project screencast Paul Groth (VU University Amsterdam) Watch presentation video Read presentation notes
Publication: Toxins in transit
The Pharmacoinformatics Research Group seeks to further understanding of transporter proteins and their interactions with drugs, with a particular focus on multidrug resistance in cancer. The development of the eTOX and Open PHACTS databases should encourage greater integration of pharmacoinformatics datasets so that more efficient in silico models can be…
Open PHACTS API 1.3 released
We are excited to release the Open PHACTS API 1.3. Among the features are: Over 2,900 million triples New compound API calls: drug type (approved, experimental) New pharmacology API calls: pChEMBL, assay type, generic name, literature DOI/PMID, target type and component New target info API calls: ChEMBL URIs, UniProt protein-protein interactions,…
Publication: Applying Linked Data Approaches to Pharmacology: Architectural Decisions and Implementation
The discovery of new medicines requires pharmacologists to interact with a number of information sources ranging from tabular data to scientific papers, and other specialized formats. In this application report, we describe a linked data platform for integrating multiple pharmacology datasets that form the basis for several drug discovery applications….
The Open PHACTS Foundation joins the project
We are pleased to announce that the Open PHACTS project’s successor organisation, the Open PHACTS Foundation, has joined the project as a partner. The Open PHACTS Foundation aims to ensure the sustainability of the Open PHACTS Discovery Platform infrastructure. Furthermore, it acts as a hub for scientific research and development relevant…
Conference: 5th Annual aDREAM Conference
5th Development of Robust Experimental Assay Methods (aDREAM) Conference, Madison, USA Linda Zander-Balderud (AstraZeneca) gave a presentation: Applying BioAssay Ontology to facilitate HTS analysis
Presentation: Applying BioAssay Ontology to facilitate HTS analysis
5th Development of Robust Experimental Assay Methods (aDREAM) Conference, Madison, USA Linda Zander-Balderud (AstraZeneca) View presentation
Publication: Nanopublication Guidelines
This document describes the structure of nanopublications and offers guidelines in their composition, implementation and use. It was produced by members of the Concept Web Alliance (CWA), an open collaborative community that is actively addressing the challenges associated with the production, management, interoperability and analysis of unprecedented volumes of data….
Conference: ERCIM 2013
ERCIM 2013, London, UK Open PHACTS participated in the 6th International Conference of the ERCIM Working Group on Computational and Methodological Statistics
Conference: SWAT4LS 2013
International SWAT4LS Workshop 2013, Edinburgh, Scotland Núria Queralt (Universitat Pompeu Fabra) presented a poster: DisGeNET RDF: A gene-disease association Linked Open Data resource Alasdair Gray (Heriot-Watt University) gave a presentation: Computing Identity Co-reference Across Drug Discovery Datasets Ian Dunlop (University of Manchester) presented a publication: Open PHACTS Explorer: Bringing the web to the semantic…
Award-winning Open PHACTS publications
Open PHACTS publications won the top two best paper awards at SWAT4LS 2013: Computing Identity Co-Reference Across Drug Discovery Datasets (Christian Y.A. Brenninkmeijer, Ian Dunlop, Carole Goble, Alasdair J.G. Gray, Steve Pettifer and Robert Stevens) Nanopublications for exposing experimental data in the life-sciences: a Huntingtion’s Disease case study (Eleni Mina, Mark…