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Publication: Using the BioAssy Ontology for Analyzing High-Throughput Screening Data

High-throughput screening (HTS) is the main starting point for hit identification in drug discovery programs. This has led to a rapid increase of available screening data both within pharmaceutical companies and the public domain. We have used the BioAssay Ontology (BAO) 2.0 for assay annotation within AstraZeneca to enable comparison…

Job Opportunity: OPF Technical and Strategic Coordinator

On December 9, 2014, Posted by , In News, By ,, , With No Comments

An exciting opportunity for an experienced pharma/life-science professional to join the Open PHACTS Foundation as technical strategic co-ordinator. For more information, please see the job listing.

Open PHACTS added to the OMICtools directory

On December 9, 2014, Posted by , In News, By ,, , With No Comments

Open PHACTS has been added to the OMICtools directory of resources for biomedical researchers: http://omictools.com/open-phacts-s7428.html

Conference: DTL On Track

DTL On Track (DTL and ELIXIR-NL kickoff), Amersfoort, the Netherlands Paul Groth (VU University Amsterdam) represented Open PHACTS

Conference: EKAW 2014

EKAW 2014, The 19th International Conference on Knowledge Engineering and Knowledge Management, Linköping, Sweden Stefan Schlobach (VU University Amsterdam) represented Open PHACTS

Human Proteome data in RDF format

We are excited that Open PHACTS team members’ experience helped make Human Proteome data available in RDF format: http://www.proteinatlas.org/about/download

Conference: Bring Your Own Data: Rare Disease Registries

Bring Your Own Data: Rare Disease Registries (and biobanks), Rome, Italy Núria Queralt-Rosinach (Hospital del Mar Medical Research Institute) attended as a linked data expert

Conference: eResearch Africa 2014

eResearch Africa 2014, Cape Town, South Africa Barend Mons (LUMC) represented Open PHACTS

Open PHACTS Foundation participates in Horizon 2020

On November 25, 2014, Posted by , In News, By ,, , With No Comments

The Open PHACTS Foundation will be participating in Big Data Europe’s Horizon 2020 project, which aims to integrate existing big data infrastructures into an extensible stack of semantically interoperable, large-scale, multi-lingual data assets. Part of the Foundation’s role will involve running pilots on services combining data and functionalities from the Open…

Conference: 6th Spanish Drug Discovery Network (SDDN) Meeting

6th Spanish Drug Discovery Network (SDDN) Meeting, Madrid, Spain Bryn Williams-Jones (Connected Discovery) gave a presentation: The Open PHACTS Discovery Platform: Semantic Data Integration for Life Sciences

Presentation: The Open PHACTS Discovery Platform: Semantic Data Integration for Life Sciences

6th Spanish Drug Discovery Network (SDDN) Meeting, Madrid, Spain Bryn Williams-Jones (Connected Discovery) View presentation

Publication: Drug Discovery FAQs: Workflows for answering cross concept drug discovery questions

On November 20, 2014, Posted by , In Publications, With No Comments

Modern data-driven drug discovery requires integrated resources to support decision-making and enable new discoveries. The Open PHACTS Discovery Platform (http://dev.openphacts.org) was built to address this requirement by focusing on drug discovery questions that are of high priority to the pharmaceutical industry. Although complex, most of these frequently asked questions (FAQs)…

Publication: On the formulation of performant SPARQL queries

The combination of the flexibility of RDF and the expressiveness of SPARQL provides a powerful mechanism to model, integrate and query data. However, these properties also mean that it is nontrivial to write performant SPARQL queries. Indeed, it is quite easy to create queries that tax even the most optimised…

Conference: BrazMedChem 2014

BrazMedChem 2014, the 7th Brazilian Symposium on Medicinal Chemistry, Campos do Jordão, Brazil Antony Williams (Royal Society of Chemistry) represented Open PHACTS

Open PHACTS API: 40 million hits in November

On November 11, 2014, Posted by , In News, By , With No Comments

An amazing new record – over 40 million hits were recorded on the Open PHACTS API in November 2014! Find out more about the API at dev.openphacts.org,

Project Meeting: Project & Science Forum

On November 6, 2014, Posted by , In Project Meetings, By , With No Comments

Open PHACTS Project & Science Forum (Mölndal, Sweden)

Project Meeting: Steering Committee

On November 6, 2014, Posted by , In Project Meetings, By , With No Comments

8th Steering Committee meeting (Mölndal, Sweden)

Conference: SICSA DEMOfest 2014

SICSA DEMOfest 2014, Edinburgh, UK Alasdair Gray (Heriot-Watt University) gave a presentation: The Open PHACTS Discovery Platform

Presentation: The Open PHACTS Discovery Platform

SICSA DEMOfest 2014, Edinburgh, UK Alasdair Gray (Heriot-Watt University) View presentation

Open PHACTS welcomes EdgeLeap as an Associated Partner

On October 27, 2014, Posted by , In News, By ,, , With No Comments

Open PHACTS extends a warm welcome to our new Associated Partner EdgeLeap. A full list of Associated Partners can be found here. Find out more about how you can get involved with Open PHACTS!

Conference: Drug Discovery USA Congress 2014

Drug Discovery USA Congress 2014, Boston, USA Tom Plasterer (AstraZeneca) gave a presentation: The Big Data Integration Myth

Presentation: Help me describe my data: A demonstration of the Open PHACTS VoID Editor

On October 20, 2014, Posted by , In Presentations, By ,,, , With No Comments

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy Alasdair Gray (Heriot-Watt University) View presentation | Paper

Presentation: Capturing Provenance for a Linkset of Convenience

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy Simon Jupp (European Bioinformatics Institute) View presentation

Presentation: Scientific Lenses to Support Multiple Views over Linked Chemistry Data

On October 20, 2014, Posted by , In Presentations, By ,,, , With No Comments

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy Alasdair Gray (Heriot-Watt University) View presentation See also: Full publication: Scientific Lenses to Support Multiple Views over Linked Chemistry Data

Presentation: A Justification-based Semantic Framework for Representing, Evaluating and Utilizing Terminology Mappings

On October 19, 2014, Posted by , In Presentations, By ,,, , With No Comments

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy Kerstin Forsberg (AstraZeneca) View presentation

Publication: Scientific Lenses to Support Multiple Views over Linked Chemistry Data

When are two entries about a small molecule in different datasets the same? If they have the same drug name, chemical structure, or some other criteria? The choice depends upon the application to which the data will be put. However, existing Linked Data approaches provide a single global view over…

Conference: ISWC 2014

On October 19, 2014, Posted by , In Conferences, By ,, , With No Comments

ISWC 2014, The 13th International Semantic Web Conference, Trentino, Italy The Open PHACTS Foundation sponsored this conference, and Open PHACTS representatives gave several presentations

Conference: 6th International Symposium on Semantic Mining in Biomedicine

6th International Symposium on Semantic Mining in Biomedicine (SMBM), Aveiro, Portugal Laura I. Furlong, Alex Bravo, Janet Piñero, Núria Queralt-Rosinach and Michael Rautschka (Parc de Salut Mar Barcelona) presented BeFree: a text mining system to extract relations between genes, diseases and drugs for translational researc

Conference: IMI 2 Open Info Day

IMI 2 Open Info Day, Brussels, Belgium Christine Chichester (Swiss Institute of Bioinformatics) represented Open PHACTS.

Conference: XII Symposium on Bioinformatics

XII Symposium on Bioinformatics, Sevilla, Italy Janet Piñero (Parc de Salut Mar Barcelona) presented a poster: DisGeNET: a discovery platform for the exploration of human diseases and their genes